Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...
Mar 1, 2023
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New research from the University of Michigan Rogel Cancer Center reveals that the metabolic pathways that make a specific type of T cell function are different than previously believed. The key to this discovery lies in a ...
Feb 18, 2023
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Heart failure is often identified only when the heart has already deteriorated. This is in large part because the cause is unknown for about 70% of people who experience heart failure.
Feb 13, 2023
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Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.
Feb 13, 2023
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Neuropathic pain is a type of chronic pain caused by damage to the nervous system due mainly to metabolic diseases such as diabetes and arthritis, or the side effects of some kinds of chemotherapy. It is believed to affect ...
Jan 10, 2023
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Lactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis and autoimmune diseases, which is known as the Warburg effect. Despite being an important metabolic ...
Jan 4, 2023
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As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...
Nov 14, 2022
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The way that tumor cells enable their uncontrolled growth is also a weakness that can be harnessed to treat cancer, researchers at the University of Michigan and Indiana University have shown.
Sep 21, 2022
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The locus coeruleus is among the first brain regions to degenerate in Alzheimer's and Parkinson's disease, physicians and scientists have known. But why this area is so vulnerable is less understood.
Sep 1, 2022
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In their recent publication in Cell Reports, a team of scientists, led by Xiling Shen, Ph.D., chief scientific officer at the Terasaki Institute for Biomedical Innovation (TIBI), has demonstrated the pivotal role of an enzyme, ...
Jul 5, 2022
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