Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

Medical research

Understanding and targeting prostate cancer metabolism

South Australian medical researchers have identified a new way in which prostate cancer cells use glucose to grow and survive, which in turn could be the secret to destroying them.

Medical research

Researchers discover a new pathway to tackle follicular lymphoma

In order to grow beyond control, tumors manipulate cell signals to make it appear as if the cells have the nutrients they need. That is the case in follicular lymphoma, a type of tumor that affects the B lymphocytes of the ...

Immunology

Tuning the immune system may enhance vaccines and ease disease

Immunologists at St. Jude Children's Research Hospital have identified a biological pathway that selectively controls how key immune cells, called T follicular helper cells, mature into functional components of the immune ...

Diseases, Conditions, Syndromes

Sex-specific immune response in COVID-19 linked to cellular metabolism

Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing ...

Medical research

Enhanced autophagy could help treat diabetes

Enhancing autophagy—the cellular process that breaks down and removes unneeded components—in fat tissue could help treat diabetes, according to a Northwestern Medicine study published in Cell Reports.

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