Oncology & Cancer

Study challenges long-standing concept in cancer metabolism

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

Diseases, Conditions, Syndromes

Faulty gene linked to obesity in adults

Groundbreaking new research linking obesity and metabolic dysfunction to a problem in the energy generators in cells has been published by researchers from the Harry Perkins Institute of Medical Research and The University ...

Oncology & Cancer

Metabolism drives growth and division of cancer cells

The metabolic state of tumor cells contributes to signals that control their proliferation. German biochemist and Nobel Prize laureate Otto H. Warburg observed in the 1920s that tumor cells radically change their metabolism. ...

Cardiology

Study gets to the heart of heart failure

A failing heart is said to be like an "engine out of fuel." To better understand the problem of energy production in heart-failure patients, researchers at Yale University and Duke University studied the underlying metabolic ...

Diabetes

New associations between genes and metabolic markers

In two comprehensive studies, scientists from the Helmholtz Zentrum München (HMGU), Ludwig-Maximilians-Universität München (LMU) and Technische Universität München (TUM) have discovered new associations of two major ...

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