Neuroscience

Lipid epoxides target pain, inflammatory pathways in neurons

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, ...

Diseases, Conditions, Syndromes

Physical frailty syndrome: A cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related ...

Oncology & Cancer

Researchers seek insights into cancer's hidden vulnerabilities

One of the biggest challenges to the development of medical treatments for cancer is the fact that there is no single kind of cancer. Cancers derive from many kinds of cells and tissues, and each have their own characteristics, ...

Immunology

Molecular 'switch' reverses chronic inflammation and aging

Chronic inflammation, which results when old age, stress or environmental toxins keep the body's immune system in overdrive, can contribute to a variety of devastating diseases, from Alzheimer's and Parkinson's to diabetes ...

Diseases, Conditions, Syndromes

Mapping the pathway to gut health in HIV and SIV infections

A UC Davis study found that the damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus, was rapidly repaired within five hours of receiving Lactobacillus ...

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