Medical research

Models for exploring the development of brain metastasis

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated with cancer. Now, a new study led by Cláudia C. Faria, principal investigator ...

Medical research

Breast cancer: Why metastasis spreads to the bone

When cancer cells break away from a primary tumor and migrate to other organs, this is called "metastatic cancer." The organs affected by these metastases, however, depend in part on their tissue of origin. In the case of ...

Oncology & Cancer

T-cell interactions vary between tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according ...

Oncology & Cancer

Scientists discover part of the origins of metastasis

Metastatic cells occur in many forms of cancer. They originate in primary tumors and then break away and migrate. They travel through the tissues surrounding them, through blood vessels or lymphatic channels. Along the way, ...

Oncology & Cancer

Neural stem cell therapy may improve metastatic cancer survival

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according ...

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