A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer. One of the key features involves changes in the immune system that ...
Jan 9, 2023
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Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage to form new tumors, and so remain dormant. The deadliest cancer cells are ...
Jan 5, 2023
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High levels of ammonia in tumors leads to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed. Researchers found that ...
Dec 23, 2022
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A new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year clinical trial at the University of Colorado Cancer Center.
Dec 16, 2022
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A patient's own immune cells, multiplied into an army of billions of immune cells in a lab, can be used as a living medicine against metastatic melanoma, an aggressive form of skin cancer, as the TIL trial has shown. The ...
Dec 8, 2022
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Residual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated with neoadjuvant chemotherapy (NAC) had a higher score of a biomarker of distant metastatic recurrence than ...
Dec 6, 2022
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One of the most puzzling—and devastating—aspects of cancer is its potentially lethal wanderlust, the spread of the disease from a primary tumor to a new and distant site.
As cancers grow and potentially spread to new parts of the body, they often shed cells and DNA into the blood stream. DNA can be analyzed for both the amount of DNA present and whether any potential mutations exist that may ...
Nov 29, 2022
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Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers at Chalmers have shown that these metastatic cancers, that spread from the original, adapt their ...
Nov 17, 2022
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Nectin-4 has been successfully established as a target molecule in locally advanced and metastatic bladder cancer. An antibody-drug conjugate (enfortumab-vedotin) directed against nectin-4 has shown marked tumor remission ...
Nov 3, 2022
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