A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast ...
Nov 25, 2014
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In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous ...
Nov 7, 2014
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Mohamed Bentires-Alj and his team at the Friedrich Miescher Institute for Biomedical Research (FMI) together with scientists from the Novartis Institutes for BioMedical Research (NIBR) show in a study published today in Nature ...
Oct 23, 2014
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The genetic fingerprint of a metastatic cancer is constantly changing, which means that the therapy that may have stopped a patient's cancer growth today, won't necessarily work tomorrow. Although doctors can continue to ...
Oct 8, 2014
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Within the first 5 years after the birth of a child, women are at an increased risk of developing metastatic breast cancer. Women diagnosed with postpartum breast cancer have a decreased disease free survival time compared ...
Sep 24, 2014
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A new study by University of Kentucky researchers has identified a novel molecule named Arylquin 1 as a potent inducer of Par-4 secretion from normal cells. Par-4 is a protein that acts as a tumor suppressor, killing cancer ...
Sep 15, 2014
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Metastatic melanoma is a highly aggressive skin cancer whose incidence is on the rise at an alarming rate. Research has revealed that metastatic tumor cells share similar signaling pathways with embryonic stem cells to sustain ...
Sep 15, 2014
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Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network ...
Sep 11, 2014
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Circulating tumor cell (CTC) clusters – clumps of from 2 to 50 tumor cells that break off a primary tumor and are carried through the bloodstream – appear to be much more likely to cause metastasis than are single CTCs, ...
Aug 28, 2014
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For the first time an oncogenic somatic mutation at amino acid 918 in the RET (rearranged during transfection) protein has been identified in small cell lung cancer (SCLC) tumors and enforced expression of this mutation within ...
Aug 22, 2014
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