By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
May 21, 2013
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Published today in Cancer Cell, results of a study directed by Joaquin Mateo, Head of the Vall d'Hebron Institute of Oncology's (VHIO) Prostate Cancer Translational Research Group, show that DNA/RNA material contained in ...
Jul 8, 2024
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Early detection is key for managing metastatic brain cancer. Above, a secondary brain tumor originating from melanoma skin cancer.
Mar 14, 2018
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Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, ...
Dec 12, 2017
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As the field of liquid biopsies for tracking disease progression and therapeutic response heats up, many doctors are looking for ways to apply this approach to their patients. Currently, assays for circulating tumor cells ...
Sep 24, 2015
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A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does not require prior ...
Apr 3, 2013
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Scientists at the Johns Hopkins Kimmel Cancer Center have identified a molecular partnership in pancreatic cancer cells that might help to explain how the disease spreads—metastasizes—in some cases. Their findings reveal ...
Aug 10, 2015
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Obesity is the second-leading preventable cause of cancer and represents one of the greatest threats to global human health. But it has not been clear exactly how whole-body metabolism affects tumor formation. In particular, ...
Apr 9, 2018
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A symposium presented at the American Association for Cancer Research Annual Meeting 2016 offers updated results on the ongoing phase 1b clinical trial of anti-PDL1 immunotherapy atezolizumab in advanced stage colorectal ...
Apr 18, 2016
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Chromosomal errors are a hallmark of cancer cells. Defects in the genome derived from the incorrect separation of chromosomes (and the DNA packed within) in each division of cells drive tumor growth and resistance to therapy.
Apr 24, 2023
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