National University of Singapore researchers developed an approach to target highly resistant triple-negative breast cancers (TNBCs) by interfering with their energy production using cytotoxic gold-metformin prodrugs.
Apr 22, 2021
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17
The anti-diabetic drug phenformin may prompt stronger cancer-fighting activities than its sister compound metformin, a finding that could have major implications for current and future clinical trials investigating both agents ...
Apr 14, 2021
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15
Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) ...
Apr 14, 2021
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6
Radiation can be life-saving for a child with a brain tumor. But this therapy can also cause damage to the brain that leaves the child with deficits in cognitive function, including learning and memory challenges.
Apr 7, 2021
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149
A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems ...
Mar 29, 2021
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136
A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin—a drug commonly used to treat Type 2 diabetes—can successfully reduce ...
Mar 29, 2021
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279
Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University ...
Mar 18, 2021
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32
A study of 44,541 women has found that there appears to be no association between type 2 diabetes and developing breast cancer overall. This may be because most women in the study with type 2 diabetes were taking metformin, ...
Jan 29, 2021
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7
Use of the diabetes drug metformin—before a diagnosis of COVID-19—is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University ...
Jan 14, 2021
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901
University of Minnesota Medical School and UnitedHealth Group researchers found that metformin was associated with significantly reduced COVID-19 death risks in women in one of the world's largest observational studies of ...
Dec 4, 2020
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