(HealthDay)—The addition of tofacitinib to rheumatoid arthritis (RA) treatment regimens improves patient response to non-biologic disease-modifying antirheumatic drugs (DMARDs), according to a study published in the Aug. ...
Aug 22, 2013
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The tyrosine kinase inhibitor afatinib significantly improved progression-free survival compared to methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after failure of platinum-based ...
Sep 27, 2014
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St. Jude Children's Research Hospital scientists have identified factors that influence how children with acute lymphoblastic leukemia (ALL) respond to methotrexate. High-dose methotrexate is a part of modern curative therapy ...
Nov 10, 2020
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(HealthDay)—For patients with rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) with prior nonmelanoma skin cancer (NMSC), the risk of second NMSC varies with different treatments, according to a study published ...
Oct 29, 2015
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For patients with hand osteoarthritis and synovitis, methotrexate has a potentially clinically meaningful effect on reducing pain, with no increase in adverse events, according to a study published online Oct. 12 in The Lancet.
Nov 6, 2023
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In February, the United States came within weeks of running out of preservative-free methotrexate, a generic drug that is an essential component of chemotherapy treatments for the most common childhood cancer, acute lymphoblastic ...
Apr 24, 2012
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Women whose first pregnancy is ectopic are likely to have fewer children in the following 20-30 years than women whose first pregnancy ends in a delivery, miscarriage or abortion, according to results from a study of nearly ...
Oct 17, 2012
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The treatment of moderately active rheumatoid arthritis with the tumour necrosis factor inhibitor Etanercept achieves excellent success in more than 80 per cent of patients. With this method, the success can be maintained ...
Jan 18, 2013
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(HealthDay)—Compared to clinical diagnosis of synovitis, ultrasound-detected synovitis provides either improved sensitivity or specificity when used with the American College of Rheumatology/European League Against Rheumatism ...
May 15, 2013
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(HealthDay)—Biologics seem to be associated with greater reduction in psoriasis severity scores and higher drug survival rates than methotrexate in pediatric patients treated in a real-world setting, according to a study ...
Feb 10, 2020
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