Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma. Additionally, they report results of the ...
Jan 27, 2021
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Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time—around ...
Jan 4, 2021
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By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...
Dec 24, 2020
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SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...
Dec 23, 2020
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Our ability to feel and understand the emotions of others, "empathy," is at the core of our prosocial behaviors such as cooperation and caregiving. Scientists have recognized two types of empathy: cognitive and affective. ...
Dec 8, 2020
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Harvard Medical School scientists have successfully restored vision in mice by turning back the clock on aged eye cells in the retina to recapture youthful gene function.
Dec 2, 2020
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In a comprehensive analysis of patients with cancer who had exceptional responses to therapy, researchers have identified molecular changes in the patients' tumors that may explain some of the exceptional responses. The results ...
Nov 19, 2020
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Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to ...
Nov 18, 2020
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Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting ...
Oct 26, 2020
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A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD). This signature mark spanned ...
Oct 22, 2020
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