Genetics

Possible role for Huntington's gene discovered

About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA repeats in the middle ...

Genetics

Researchers characterize epigenetic fingerprint of 1,628 people

Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show ...

Medical research

Maternal smoking causes changes in fetal DNA

Children whose mothers or grandmothers smoked during pregnancy are at increased risk of asthma in childhood, but the underlying causes of this are not well understood. Now a new study indicates changes in a process called ...

Genetics

Big data opens up vast frontiers in genetic research

Professor Ryan Lister from University of Western Australia is using big data to examine DNA in new ways that could greatly increase the understanding of the human body and improve agricultural techniques.

Oncology & Cancer

Older biologic age linked to elevated breast cancer risk

Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. Biologic age was determined by measuring DNA methylation, ...

Psychology & Psychiatry

Epigenetic changes at birth could explain later behavior problems

Epigenetic changes present at birth - in genes related to addiction and aggression - could be linked to conduct problems in children, according to a new study by King's College London and the University of Bristol.

Diabetes

ASN: Bardoxolone methyl no benefit in T2DM, stage 4 CKD

(HealthDay)—Bardoxolone methyl does not reduce the risk of end-stage renal disease (ESRD) or cardiovascular death in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, according to a study published ...

Psychology & Psychiatry

Scientists gain new understanding of how brain cells talk

Experts from the University of Nottingham have discovered that reversing the modification of molecular messages at synapses in the human brain, may contribute to reversible mental health conditions such as anxiety, and memory ...

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