A new University of California, Irvine-led study finds a new method for identifying biomarkers may aid in early cancer diagnosis. The study focused on lung cancer, however the Cell Heterogeneity-Adjusted cLonal Methylation ...
Jan 27, 2021
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Treatment of depression faces two main challenges. The first is that almost 50% of patients do not respond well to existing antidepressants. The second is that conventional medications take a relatively long time—around ...
Jan 4, 2021
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By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic ...
Dec 24, 2020
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Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to ...
Nov 18, 2020
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Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting ...
Oct 26, 2020
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Tumors of the pancreas are particularly feared. They are usually discovered late and mortality is high. Until now, no targeted and personalized therapies exist. Scientists at the German Cancer Research Center (DKFZ) and the ...
Oct 15, 2020
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A one-two punch of changing gene expression, then deploying immune checkpoint inhibitors, shows promise in battling one of the most treatment-resistant types of cancer in preclinical models, according to a new publication ...
Sep 30, 2020
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Epigenetic changes in the islets of Langerhans of the pancreas can be detected in patients several years before the diagnosis of type 2 diabetes (T2D). These changes are responsible for the altered methylation activity of ...
Sep 10, 2020
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Children born to mothers who had diabetes during pregnancy may age faster biologically and be at an increased risk for obesity and high blood pressure, according to Rutgers researchers.
Sep 10, 2020
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A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only ...
Aug 5, 2020
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