Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity. Life style and environmental factors ...
Mar 20, 2017
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Fragile X syndrome, the most common heritable cause of intellectual disability and a frequent cause of autism, is characterized by abnormalities of the FMR1 gene that are difficult to analyze. Preclinical studies of Fragile ...
Aug 12, 2016
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(HealthDay)—Age and obesity affect gene regulation in men with symptomatic benign prostatic hyperplasia, according to a study published in the October issue of The Journal of Urology.
Sep 26, 2015
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The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference revealed that DNA methylation - a mechanism that regulates gene expression - could influence the ...
Jun 12, 2015
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DNA profiling (or genetic fingerprinting) has proved a revolutionary tool for forensic investigators as a means to identify potential suspects, exonerate the innocent and convict the guilty. But, like any forensic technique, ...
Apr 2, 2015
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Researchers have identified and validated two DNA methylation markers that could help physicians to more accurately determine a patient's response to epigenetic drugs for treatment of myelodysplastic syndromes (MDS), according ...
Apr 8, 2013
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(Medical Xpress)—A University of British Columbia and Centre for Molecular Medicine and Therapeutics (CMMT) study has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, ...
Oct 18, 2012
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Further exploration into the endpoints of the NRG Oncology/RTOG 0424 trial resulted in the discovery that MGMT promoter methylation is an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide ...
Jul 5, 2018
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