Immunology

Obesity impairs immune cell function, accelerates tumor growth

Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival. Over the years, scientists have identified obesity-related processes that drive tumor growth, ...

Oncology & Cancer

New prognostic markers for colon cancer identified

Gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs). Additionally, researchers have ...

Oncology & Cancer

A better test for the tumor-targeting of CAR-T therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies, in which the immune system's T cells are extracted from a ...

Medical research

Tumor progression depends on the tumor microenvironment

Tumor cells constantly interact with the cellular environment they live in, affecting tumor progression and metastasis. In a new study, researchers from Tokyo Medical and Dental University (TMDU) and Niigata University discovered ...

Oncology & Cancer

Markers may predict patient response to immune therapy of cancer

For many individuals with different types of cancer, immune checkpoint inhibitors can effectively boost their immune system to fight their disease, but not all patients benefit from these medications. Now a team led by investigators ...

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