A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.
Nov 8, 2019
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Research led by North Carolina State University has found that when enteric glial cells are exposed to secretions from colon tumors, the glial cells convert into promoters of tumor growth. The work demonstrates enteric glial ...
Oct 30, 2019
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Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) report a discovery that helps scientists understand why some ...
Oct 23, 2019
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that ...
Sep 25, 2019
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Cancer researchers are setting their sights on a new kind of cancer treatment that targets the tumor's surrounding environment, called the tumor microenvironment, in contrast to targeting the tumor directly.
Sep 4, 2019
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The healthy cells immediately surrounding a tumour become more stem cell-like and support cancer growth, reveals a new study published in Nature.
Aug 28, 2019
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In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy. To better understand the specific ...
Aug 26, 2019
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Known as two of the most lethal cancers, ovarian and pancreatic cancer are often called silent killers since they rarely have early symptoms. As a result, they frequently go undetected until they're too late to effectively ...
Jul 22, 2019
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Researchers at the University of Notre Dame have outlined the delivery mechanism tumor cells use to move nucleic acids into small sacs shed from their surfaces—information that is eventually shared with other cells within ...
Jul 12, 2019
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The tumor microenvironment (TME) is a mix of fluids, immune cells and blood vessels which envelops the tumors. Interactions between tumor cells and the TME determine the progression and fate of tumors. Therefore, understanding ...
Jul 8, 2019
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