A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.
Dec 18, 2020
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Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival. Over the years, scientists have identified obesity-related processes that drive tumor growth, ...
Dec 9, 2020
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The labyrinth of jumbled blood vessels in the tumor microenvironment remains one of the toughest blockades for cellular therapies to penetrate and treat solid tumors. Now, in a new study published online today in Nature Cancer, ...
Nov 30, 2020
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An evolving understanding of cancer that incorporates the physical properties of tumors and their surrounding tissues into existing biologic and genetic models can direct cancer researchers down previously uncharted avenues, ...
Oct 30, 2020
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For many individuals with different types of cancer, immune checkpoint inhibitors can effectively boost their immune system to fight their disease, but not all patients benefit from these medications. Now a team led by investigators ...
Sep 7, 2020
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If cancer is a series of puzzles, a new study pieces together how several of those puzzles connect to form a bigger picture.
Sep 2, 2020
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Working with an international team of researchers, HonorHealth Research Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, were instrumental in one of the first clinical trials ...
Aug 11, 2020
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Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in its natural microenvironment ...
Aug 5, 2020
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Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response. The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of ...
Jul 11, 2020
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Aggregates of immune cells known as tertiary lymphoid structures (TLSs), seen here within a tumor of the soft tissues known as a rhabdomyosarcoma, are major players in the immune system's fight against cancer. Johns Hopkins ...
Jun 26, 2020
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