A new study reveals the mechanisms whereby low dose photodynamic therapy affects the microstructure of vessels. Using co-cultures of pericytes and endothelial cells in vitro, the authors show that low dose photodynamic therapy ...
Apr 5, 2019
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Columbia researchers have learned why some glioblastomas—the most common type of brain cancer—respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy ...
Feb 15, 2019
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(HealthDay)—Neoadjuvant administration of programmed cell death protein 1 (PD-1) blockade seems to enhance local and systemic antitumor immune response in glioblastoma, according to a study published online Feb. 11 in Nature ...
Feb 13, 2019
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Immunotherapies that take off the "brakes" on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change.
Jan 17, 2019
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As the second leading cause of death worldwide, cancer is a focal point in both clinical research and health care fields, but not all cancers are created equal. While some cancers are now much less deadly due to recent medical ...
Jan 14, 2019
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Research led by Suresh Alahari, Ph.D., the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has found a new role for a protein discovered by his lab in preventing the ...
Jan 11, 2019
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Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people ...
Dec 18, 2018
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Imagine being at a packed concert hall with a mosh pit full of dancers creating a wall against outsiders. When targeted drugs try to make their way toward a pancreas tumor, they encounter a similar obstacle in stiff tissue ...
Dec 6, 2018
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The maintenance workers of the vascular system, pericyte cells envelop the surface of blood vessels, supporting their stability, growth and survival. Given that blood vessel growth is one necessary component in tumor development ...
Aug 31, 2018
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The advent and advancement of T cell therapy, especially chimeric antigen receptor (CAR)-modified T cells, has demonstrated therapeutic potential in treating previously treatment-resistant tumors. However, few CAR targets ...
Jun 27, 2018
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