Oncology & Cancer

Tracking tumor cells and unraveling hidden information

tumor cells circulating in the blood of cancer patients are important markers for early diagnosis, treatment success and patient prognosis. But since so few circulate, identifying them is a challenge. Thanks to artificial ...

Oncology & Cancer

Hybrid microscope could bring digital biopsy to the clinic

By adding infrared capability to the ubiquitous, standard optical microscope, researchers at the University of Illinois at Urbana-Champaign hope to bring cancer diagnosis into the digital era.

HIV & AIDS

How HIV develops resistance to key drugs discovered

The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research from the Crick and Dana-Farber Cancer Institute, with the findings opening the door to the development ...

Neuroscience

The highways of our brain

Researchers from the Netherlands Institute for Neuroscience (NIN) used a new technique to show how electrical impulses are traveling at high speed in the brain. It appears that myelin, the sheath around neurons, creates a ...

Immunology

Antibodies gather and form a circle for defensive attack

Antibodies play a crucial role in our immune system by linking antigen recognition with complement activation for attacking foreign cells. Using high-speed atomic force microscopy, collaborative groups, including researchers ...

Radiology & Imaging

Combination of microscopy techniques makes images twice as sharp

Researchers at Delft University of Technology have combined two existing super-resolution microscopy techniques to create a new method. Many experts thought that combining these techniques was not technically possible. The ...

Neuroscience

Study reveals mysteries of critical brain receptor complex

Glutamate receptors in the brain called AMPARs are critical for synaptic plasticity, learning and memory. Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, ...

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Microscopy

Microscopy is the technical field of using microscopes to view samples or objects. There are three well-known branches of microscopy, optical, electron and scanning probe microscopy.

Optical and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation/electron beam interacting with the subject of study, and the subsequent collection of this scattered radiation in order to build up an image. This process may be carried out by wide-field irradiation of the sample (for example standard light microscopy and transmission electron microscopy) or by scanning of a fine beam over the sample (for example confocal laser scanning microscopy and scanning electron microscopy). Scanning probe microscopy involves the interaction of a scanning probe with the surface or object of interest. The development of microscopy revolutionized biology and remains an essential tool in that science, along with many others including materials science and numerous engineering disciplines.

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