Ophthalmology

Novel mechanism of retinal degeneration

Photoreceptors, like polarized sensory neurons, are essential for light sensation and phototransduction, which are highly dependent on the photoreceptor cilium. Disruption of photoreceptor cilia has been implicated in a variety ...

Medical research

Researchers uncover molecular details of muscle contraction

The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while ...

Pediatrics

An innovative test to diagnose Chagas disease in newborns

An innovative test that combines a DNA extraction system inspired by a modified 3D printer (PrintrLab) with loop-mediated isothermal molecular amplification (LAMP) could be used to detect T. cruzi infection—responsible ...

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Microscopy

Microscopy is the technical field of using microscopes to view samples or objects. There are three well-known branches of microscopy, optical, electron and scanning probe microscopy.

Optical and electron microscopy involve the diffraction, reflection, or refraction of electromagnetic radiation/electron beam interacting with the subject of study, and the subsequent collection of this scattered radiation in order to build up an image. This process may be carried out by wide-field irradiation of the sample (for example standard light microscopy and transmission electron microscopy) or by scanning of a fine beam over the sample (for example confocal laser scanning microscopy and scanning electron microscopy). Scanning probe microscopy involves the interaction of a scanning probe with the surface or object of interest. The development of microscopy revolutionized biology and remains an essential tool in that science, along with many others including materials science and numerous engineering disciplines.

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