Diseases, Conditions, Syndromes

Connecting the dots in the migraine brain

A neuroimaging study recently published in the journal Cephalalgia, the official journal of the International Headache Society, shared more evidence of structural changes in the brain of migraine patients. The study, entitled ...

Neuroscience

Predictors of chronic migraine

A meta-analysis published in the journal Cephalalgia, the official journal of the International Headache Society, highlights the predictors of chronic migraine. The study, entitled "Predictors of episodic migraine transformation ...

Health

Nightly sleep disturbance linked to daily risk of migraines

Nearly half of all patients who suffer migraines report sleep disturbance as a trigger for their headaches. But the relationship between sleep and migraine headaches is not well understood or well-studied. Investigators from ...

Neuroscience

Running away from exercise: The curious case of migraine

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, highlights an overlooked relationship between migraine and exercise. The study, entitled "Anxiety sensitivity ...

Diseases, Conditions, Syndromes

Migraine prevention in children and adolescents

Cephalalgia, the official journal of the International Headache Society, published the article entitled "Cinnarizine and sodium valproate as the preventive agents of pediatric migraine: A randomized double-blind placebo-controlled ...

Medications

Got a migraine? Relief may already be on your medicine shelf

According to a new report in The American Journal of Medicine, aspirin can be considered an effective and safe option to other, more expensive medications to treat acute migraines as well as prevent recurrent attacks. A review ...

Health

How does a piece of bread cause a migraine?

Migraine is the third most prevalent illness in the world and causes suffering for tens of millions of people. In fact, nearly 1 in 4 U.S. household includes someone with migraines.

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Migraine

Migraine is a neurological syndrome characterized by altered bodily perceptions, headaches, and nausea. Physiologically, the migraine headache is a neurological condition more common to women than to men. The word migraine was borrowed from Old French migraigne (originally as "megrim", but respelled in 1777 on a contemporary French model). The French term derived from a vulgar pronunciation of the Late Latin word hemicrania, itself based on Greek hemikrania, from Greek roots for "half" and "skull". The typical migraine headache is unilateral and pulsating, lasting from 4 to 72 hours; symptoms include nausea, vomiting, photophobia (increased sensitivity to bright light), and hyperacusis (increased sensitivity to sound); approximately one third of people who suffer migraine headache perceive an aura — unusual visual, olfactory, or other sensory experiences that are a sign that the migraine will soon occur.

Initial treatment is with analgesics for the head-ache, an anti-emetic for the nausea, and the avoidance of triggering conditions. The cause of migraine headache is idiopathic; the accepted theory is a disorder of the serotonergic control system, as PET scan has demonstrated the aura coincides with diffusion of cortical depression consequent to increased blood flow (up to 300% greater than baseline). There are migraine headache variants, some originate in the brainstem (featuring intercellular transport dysfunction of calcium and potassium ions) and some are genetically disposed. Studies of twins indicate a 60 to 65 percent genetic influence upon their propensity to develop migraine headache. Moreover, fluctuating hormone levels indicate a migraine relation: 75 percent of adult patients are women, although migraine affects approximately equal numbers of prepubescent boys and girls; propensity to migraine headache is known to disappear during pregnancy, although in some women migraines may become more frequent during pregnancy.[citation needed]

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