During brain development, the precursors of nerve cells sometimes have to migrate long distances from their place of origin to their destination. In this process, proteins, such as FLRTs (pronounced "flirts"), act as guide ...
Oct 24, 2014
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During cancer metastasis, immune response cells are moving in a controlled manner through the body. Researchers from the Department of Biomedicine at the University of Basel discovered novel mechanisms of cell migration by ...
Oct 6, 2014
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(Medical Xpress)—Nancy Hynes and her group at the Friedrich Miescher Institute for Biomedical Research have discovered an important mediator of breast cancer metastasis. The protein called Memo is not only required for ...
Jun 20, 2014
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Immune cells known as neutrophils are recruited by chemical signals released from sites of injury and infection. Their primary purpose is to attack pathogens and recruit additional immune defenses, but these cells can also ...
May 21, 2014
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Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion. For the successful control of cell movement, this process ...
Mar 21, 2014
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(Medical Xpress)—If life were simple, a disease could be treated with one drug that hits one molecular target, like striking a piano key. Instead, researchers wrestle with the fact that most drugs hit multiple targets in ...
Mar 20, 2014
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The zebrafish, a tropical freshwater fish similar to a minnow and native to the southeastern Himalayan region, is well established as a key tool for researchers studying human diseases, including brain disorders. Using zebrafish, ...
Feb 18, 2014
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A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme (GBM), the most common and most aggressive form of brain cancer, after demonstrating for the first time that ...
Jan 9, 2014
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The retinoblastoma (Rb) protein plays a critical role in suppressing the multi-step process of cell migration through the bloodstream, lymphovascular invasion and the metastasis of an aggressive type of breast cancer to the ...
Dec 4, 2013
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All organisms begin life as a microscopic cluster of cells. What happens next, as they develop, is a source of endless fascination for scientists.
Dec 4, 2013
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