Psychology & Psychiatry

Mutation links bipolar disorder to mitochondrial disease

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, ...

Diseases, Conditions, Syndromes

Mitochondrial dysfunction contributes to kidney disease

Scientists found a previously unknown link between mitochondria and kidney disease, identifying a receptor that causes kidney dysfunction when suppressed, according to a study published in Proceedings of the National Academy ...

Medical research

Mitochondrial mutations and disease

Mitochondria are cellular organelles with their own DNA. Their role in power generation makes them susceptible to oxidative damage, including the formation of DNA-damaging chemical complexes called adducts.

Diseases, Conditions, Syndromes

Metabolites altered in chronic kidney disease

Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK). These individuals have a very high risk of cardiovascular ...

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