Medical research

Stopping lung damage before it turns deadly

If you've ever struggled to breathe, you've had a moment of hypoxia—a lack of oxygen. Hypoxia can have long-term effects. In fact, doctors describe hypoxia as an "initial insult."

Oncology & Cancer

Tracing a cancer's family tree to its roots reveals how tumors grow

Over time, cancer cells can evolve to become resistant to treatment, more aggressive, and metastatic—capable of spreading to additional sites in the body and forming new tumors. The more of these traits that a cancer evolves, ...

Medical research

Models for exploring the development of brain metastasis

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated with cancer. Now, a new study led by Cláudia C. Faria, principal investigator ...

Immunology

How one inflammatory disorder exacerbates another

The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...

Medical research

Liver fibrosis: The fatal signaling pathway

At least 5 million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate ...

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