Metaplasia is defined as the replacement of a fully differentiated cell type by another. There are several classical examples of metaplasia, one of the most frequent is called Barrett's esophagus. Barrett's esophagus is characterized ...
Apr 21, 2021
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Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis—a major cause of heart failure.
Jun 21, 2024
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Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife.
Dec 10, 2019
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With the school year well on its way, we all recognize the importance of getting students energized. However, we also know that overstimulated children can wreak havoc on a classroom, leaving a teacher trying to regain control ...
Oct 19, 2021
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A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can ...
Jul 9, 2021
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Even as they've revolutionized cancer treatment, drugs known as immune checkpoint inhibitors can produce a range of adverse, immune-related side effects. In a new study, scientists at Dana-Farber Cancer Institute identify, ...
Dec 16, 2022
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A group of researchers at Children's Hospital of Philadelphia (CHOP), in collaboration with Beam Therapeutics, have tested and developed an "off-the-shelf" chimeric antigen receptor T-cell (CART) using base editing, which ...
May 23, 2022
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Colorectal cancer is one of the most common types of cancer worldwide. In more than half of all cases, an important protective mechanism in cells is inactivated by mutations—the tumor suppressor gene p53. The product of ...
May 25, 2023
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Scientists have created a three-dimensional (3-D) tumor model in the laboratory for ovarian cancer that could lead to improved understanding and treatment of the disease.
Oct 2, 2020
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Researchers have identified common and rare gene mutations that increase risk for schizophrenia. Yet it's unclear what biological mechanisms go awry in the brain to cause psychosis and other disabling symptoms, due in part ...
Sep 1, 2023
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