Researchers have succeeded in establishing a mouse model that develops gastric cancer closely resembling advanced human gastric cancer. Using this model, they have discovered gastric cancer stem cells, i.e. Lgr5+ gastric ...
Dec 22, 2021
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In 2019, the WHO positioned chronic obstructive pulmonary disease (COPD) third in the global ranking of causes of death. However, some mechanisms of this debilitating chronic respiratory disease are yet to be identified. ...
Dec 14, 2021
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Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.
Dec 13, 2021
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In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune ...
Dec 9, 2021
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Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses ...
Dec 8, 2021
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Vascular diseases like atherosclerosis can lead to serious complications, like heart attack or stroke. But many treatments for these diseases target systemic risk factors, such as reducing blood pressure and cholesterol, ...
Dec 6, 2021
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Human heart muscle cells cease to multiply after birth, making any heart injury later in life a permanent one, reducing function and leading to heart failure. Now, however, Johns Hopkins Medicine researchers say they have ...
Dec 2, 2021
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Patients with heart failure often have shortness of breath and become fatigued quickly. They frequently suffer from water retention, heart palpitations, and dizziness. The condition can be triggered by a combination of elevated ...
Dec 1, 2021
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A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere. However, this process does not always take place in full. Researchers at the University of Basel ...
Nov 29, 2021
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Ludwig Maximilians University Munich (LMU) immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.
Nov 26, 2021
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