Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for ...
Jan 12, 2021
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In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don't understand. What is the role of the immune response in the process? What happens ...
Jan 11, 2021
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UT Southwestern scientists have developed a new method to study the molecular characteristics of T cells, critical immune cells that recognize and attack invaders in the body such as viruses, bacteria, and cancer.
Jan 6, 2021
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A new study from Tel Aviv University (TAU) presents an innovative treatment for deafness, based on the delivery of genetic material into the cells of the inner ear. The genetic material "replaces" the genetic defect and enables ...
Dec 23, 2020
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A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.
Dec 21, 2020
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Soon after rapamycin, the first mTOR inhibitor, emerged in 1990s as a potential treatment against unwanted cell proliferation, many cancer experts had hoped emerging drugs targeting mTOR would become a breakthrough targeted ...
Dec 21, 2020
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A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.
Dec 18, 2020
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Researchers at Karolinska Institutet in Sweden report in the journal Nature that they have developed novel first-in-class inhibitors that compromise mitochondrial function in cancer cells. Treatment with the inhibitors stopped ...
Dec 16, 2020
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In the search for new ways to treat the incurable eye disease glaucoma, researchers at Karolinska Institutet and St. Erik Eye Hospital have discovered more clues as to its pathogenesis. A new study shows how metabolic disturbance ...
Dec 15, 2020
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A protein known mostly for its role in the brain may be a key player in the cardiovascular system as well, according to a Northwestern Medicine study published in Nature.
Dec 10, 2020
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