Researchers at the National Institutes of Health developed a new mouse model that could improve the translation of research in mice into advances in human health. The mouse model, which the scientists called "wildling," acquired ...
Aug 1, 2019
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Delivering two federally approved immunity-altering drugs together significantly extended the lives of mice injected with human ovarian cancer cells, an early proof-of-concept experiment that may advance treatment for the ...
Jul 25, 2019
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Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the immune system. The investigators ...
Jul 18, 2019
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A new study by Montreal scientists published today in Nature demonstrates that a gut infection can lead to a pathology resembling Parkinson's disease (PD) in a mouse model lacking a gene linked to the human disease.
Jul 17, 2019
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In metastasis, cancer cells break away from the original tumor and take root in another region of the body by entering the blood stream. In order to spread, metastatic cells cross over the endothelium—a barrier of endothelial ...
Jul 17, 2019
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The p53 family of transcription factors (p63 and p73) plays critical roles in keratinocyte (skin cell) function.
Jul 17, 2019
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Mathematical modeling suggests that the rate at which a patient's immune system clears slow-growing variants of methicillin-resistant Staphylococcus aureus (MRSA) bacteria is a key determinant of whether antibiotics can cure ...
Jul 11, 2019
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The immune system is indispensable for defense against invading pathogens, but its aberrant activation may lead to autoimmune diseases. Regulatory T cells play a crucial role in preventing excess immune activation; mice without ...
Jul 9, 2019
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When governments and institutions deploy epidemic forecast models when facing an outbreak, they sometimes fail to factor in human behavior and over-allocate precious resources as a result. Thanks to new research authored ...
Jul 2, 2019
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Findings from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and published in the July issue of Health Affairs, shows that while the number and variety of contracts held by Accountable ...
Jul 1, 2019
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