Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.
Oct 29, 2020
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A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."
Jan 4, 2024
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Mutations in single genes can cause catastrophic diseases, such as Huntington's Disease or sickle cell anemia. However, many conditions, including cancer, diabetes and birth defects are multigenic, arising from the collective ...
Jan 31, 2013
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(HealthDay)—Hispanic/Latino (H/L) children with B-cell acute lymphoblastic leukemia (B-ALL) have an increased incidence of IKZF1 deletion and IGH-CRLF2 translocation, according to a letter to the editor published online ...
Feb 19, 2021
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Charcot-Marie-Tooth (CMT) disease is the most common form of inherited neuropathies. A genetic mutation causes the insulating myelin layer of peripheral nerves to become progressively damaged, resulting in severe disabilities ...
Jun 8, 2020
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An international team of researchers led by prof. Savvas Savvides (VIB-UGent Center for Inflammation Research) has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, ...
Jan 17, 2018
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Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses. For some 25 years ...
Jul 12, 2021
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A study led by researchers at Georgia State University provides new insights into the molecular basis of human diseases resulting from mutations in the calcium-sensing receptor (CaSR), a protein found in cell membranes.
May 31, 2016
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It is one of the ironies of sleep research that scientists stay up all night to do it.
Nov 5, 2012
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Brain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth in your brain—even if it's cancer, says Sean Grimm, MD, chief of the Section of Medical Neuro-Oncology at ...
Nov 15, 2022
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