Addiction

Opioid dependence found to permanently change brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, published Jan. 14, 2020 in PNAS, researchers ...

Diseases, Conditions, Syndromes

Bacterial link in celiac disease

Bacterial exposure has been identified as a potential environmental risk factor in developing coeliac disease, a hereditary autoimmune-like condition that affects about one in 70 Australians.

Medical research

Early prevention of neuropathic pain

An unpleasant tingling in the hands and feet, numbness, fuzzy and burning sensations—these symptoms may indicate a neuropathy, a disease of the nervous system. If the pain persists for several months, it is referred to ...

Medical research

New assay assesses multiple cellular pathways at once

A novel technological approach developed by researchers at Baylor College of Medicine expands from two to six the number of molecular pathways that can be studied simultaneously in a cell sample with the dual luciferase assay, ...

Neuroscience

The eyes are the window to the nervous system

Individuals who experience an unpleasant tingling in their hands or feet or who suffer from painful discomfort and numbness could be affected by a neuropathy—a disorder of the nervous system in which the nerve fibers become ...

Immunology

What protects killer immune cells from harming themselves?

White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from UCL and the Peter ...

Immunology

Building a better flu shot

Each year millions of Americans become sick with the flu, hundreds of thousands are hospitalized and tens of thousands die. Getting the flu shot can reduce the chances of infection. But, at best, the vaccine is only effective ...

Medical research

Investigators lead effort to create map of the human kidney

Diabetes is the leading cause of end-stage renal disease, one of the nation's most debilitating and expensive medical conditions. In 2016 Medicare spent $35 billion caring for more than 725,000 Americans whose kidneys had ...

Alzheimer's disease & dementia

Study results may provide a better understanding of Alzheimer's disease

New research suggests that the complex meshwork of proteins and potentially other biomolecules that provides structural and biochemical support to surrounding cells in the brain may play an important role in Alzheimer's disease. ...

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Molecular biology

Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Writing in Nature, William Astbury described molecular biology as:

"[...]not so much a technique as an approach, an approach from the viewpoint of the so-called basic sciences with the leading idea of searching below the large-scale manifestations of classical biology for the corresponding molecular plan. It is concerned particularly with the forms of biological molecules and[...]is predominantly three-dimensional and structural—which does not mean, however, that it is merely a refinement of morphology. It must at the same time inquire into genesis and function."

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