The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and ...
Dec 14, 2015
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The research, which has been published in the highly-regarded journal Molecular Cancer Therapeutics, suggests that peloruside A—a substance produced by the marine sponge Mycale henscheli, found mostly in Pelorus Sound—has ...
Jul 7, 2015
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Tumor treatment with multispecific antibodies is significantly more tolerable if administered subcutaneously rather than via the bloodstream, which was the standard procedure until now. This was the result of an animal model ...
Jul 1, 2015
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Cancer Research UK scientists have taken steps to overcome drug resistance in glioblastoma, the most common type of brain tumour in adults, according to research published in Molecular Cancer Therapeutics.
Jan 14, 2015
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Angiochem, a clinical stage biotechnology company creating and developing drugs that cross the blood-brain barrier, today announced the publication in Molecular Cancer Therapeutics demonstrating that ANG4043, a peptide-monoclonal ...
Dec 9, 2014
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In a second presentation looking at new ways of treating non-small cell lung cancer (NSCLC) that has both the EGFR and T790M mutations, researchers will tell the 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer ...
Nov 20, 2014
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Patients with a form of advanced colorectal cancer that is driven by a mutated version of the BRAF gene have limited treatment options available. However, results from a multi-centre clinical trial suggest that the cancer ...
Nov 20, 2014
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A new drug that targets not only common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), but also a form of the mutation that causes resistance to treatment, has shown promising results ...
Nov 19, 2014
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(Medical Xpress)—Penn State College of Medicine researchers have developed a nanoparticle to deliver a melanoma-fighting drug directly to the cancer.
Oct 23, 2014
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Researchers at the University of Auckland are using zebrafish embryos to investigate potential medicines that will inhibit the spread of some cancers via the lymphatic system.
Jul 30, 2014
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