Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths. There is a clear need to better understand the processes that enable ...
Feb 1, 2023
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Immunotherapies have improved outcomes of many patients with cancer, including melanoma. But these therapies work for only a subset of patients. Numerous studies are looking at improving responses, including research focusing ...
Jan 23, 2023
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It was previously assumed that bones lacked lymphatic vessels, but new research from the MRC Human Immunology Unit at Oxford's MRC Weatherall Institute for Molecular Medicine not only locates them within bone tissue, but ...
Jan 20, 2023
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Researchers from the University of Michigan Rogel Cancer Center have found a mechanism for why a subset of patients' tumors grow, rather than shrink, when faced with immunotherapy.
Jan 18, 2023
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A recent paper published in the Journal of Physiology deepened the case for the youthfulness-promoting effects of exercise on aging organisms, building on previous work done with lab mice nearing the end of their natural ...
Jan 17, 2023
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A Northwestern Medicine study has discovered that elevated PALI1 in advanced prostate tumors mediates crosstalk between two primary epigenetic silencing mechanisms, suggesting that dual epigenetic inhibition may be an effective ...
Dec 21, 2022
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Scientists at UC San Francisco (UCSF) have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells. The immunotherapy eliminated melanoma and pancreatic cancer in mice without ...
Dec 15, 2022
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Huntington's disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function. It is caused by a mutation in a single gene called huntingtin (HTT). More than 200,000 people ...
Dec 12, 2022
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Researchers at UC San Francisco (UCSF) have engineered molecules that act like "cellular glue," allowing them to direct in precise fashion how cells bond with each other. The discovery represents a major step toward building ...
Dec 12, 2022
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Every year, up to 1% of patients with chronic lymphocytic leukemia (CLL), a slow-growing blood cancer, have their disease transform into a far more aggressive cancer, a form of lymphoma known as Richter's syndrome. For the ...
Dec 12, 2022
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