Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...
Jun 22, 2022
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104
Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this ...
Jun 20, 2022
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56
A type of cancer treatment known as CAR T therapy has shown great promise for blood cancer treatments in the last decade, but too often, patients relapse within a short time. Now, a team of researchers has uncovered some ...
Jun 20, 2022
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Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness. In some patients, structural defects in the photoreceptor cells have been observed, ...
Jun 17, 2022
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62
A machine-learning model has helped scientists discover hundreds of genetic mutations in cancer that are undetectable by current genome sequencing, according to a study published in the journal Science Advances.
Jun 16, 2022
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Researchers in UC Santa Barbara neuroscientist Kenneth S. Kosik's lab have discovered a novel organelle—a previously unknown cell structure whose function it is to help clean up faulty proteins in times of stress and keep ...
Jun 14, 2022
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How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has ...
Jun 10, 2022
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280
Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, ...
Jun 8, 2022
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121
When someone gets an infection, most people think it's the immune system kicking into gear when they feel some of the body's natural defenses like a fever, chills, or fatigue. What most people don't know is that it's actually ...
Jun 8, 2022
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604
The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic. Researchers at Karolinska Institutet in Sweden have repurposed a cancer drug for treatment of neuroinflammatory ...
Jun 6, 2022
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