A research team led by the German Cancer Research Center in Heidelberg, Germany, has discovered that the genetic sequence of a tumor can be read like a molecular clock, traced back to its most recent common ancestor cell. ...
Fat cells store excess energy and signal these levels to the brain. In a new study this week in Nature Medicine, Georgios Paschos PhD, a research associate in the lab of Garret FitzGerald, MD, FRS director of the Institute ...
Nov 11, 2012
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Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions.
May 9, 2024
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University of Queensland-led research has revealed liver cells influence the body's internal circadian clock, which was previously believed to be solely controlled by the brain.
May 17, 2023
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New research has shown that normal human brain temperature varies much more than we thought, and this could be a sign of healthy brain function. In healthy men and women, where oral temperature is typically less than 37°C, ...
Jun 13, 2022
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A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research led by UT Southwestern ...
Aug 19, 2021
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A new study by researchers at UC Santa Cruz shows how a genetic mutation throws off the timing of the biological clock, causing a common sleep syndrome called delayed sleep phase disorder.
Oct 27, 2020
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The circadian clock system (from the Latin "circa diem," about a day) allows organisms to anticipate periodic changes of geophysical time and to adjust to those changes. Nearly all cells comprise molecular clocks that regulate ...
Jan 31, 2020
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More than 20 years ago, the lab of developmental biologist Olivier Pourquié discovered a sort of cellular clock in chicken embryos where each "tick" stimulates the formation of a structure called a somite that ultimately ...
Jan 8, 2020
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Astrocytes, 'caretaker' cells that surround and support neurons in the brain, play a much more important role in circadian rhythms, the body's 24-hour internal clock, than previously understood.
Jan 10, 2019
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