In response to seizures, the endoplasmic reticulum (ER), a network of flattened tubes in the cell that packages and transports proteins, triggers a stress response that reduces brain activity and seizure severity. The new ...
Sep 26, 2019
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Cancers evade destruction by convincing some immune cells to suppress others. But a surprising interlocutor can persuade the suppressors to defect, and the destroyers to redouble.
Sep 18, 2019
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Scientists have shed new light on how mucosal infections can affect the body's inflammatory response to shape susceptibility to recurrence.
Aug 20, 2019
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Amid the worsening Ebola outbreak in the Congo, now threatening to spill into Rwanda, a new study suggests that an existing, FDA-approved drug called nitazoxanide could potentially help contain this deadly, highly contagious ...
Aug 8, 2019
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Researchers from TARA Biosystems, Inc. and GlaxoSmithKline (GSK) today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans. The findings, published in ...
Aug 6, 2019
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Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet (LMU) team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death ...
May 1, 2019
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About 40 percent of the global population is at risk for contracting dengue—the most important mosquito-borne viral infection and a close "cousin" of the Zika virus—and yet, no effective treatment or safe licensed vaccine ...
Mar 28, 2019
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In autoimmune diseases such as psoriasis or lupus, the immune system goes into overdrive in response to people's own DNA being released from damaged cells—a reaction that can cause severe inflammation in the body.
Mar 5, 2019
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The immune response to our intestinal microbiota, the community of microorganisms that live in the human gut, ensures that these microorganisms remain in their proper place. When the intestinal immune barrier is damaged, ...
Jan 30, 2019
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Taking aim at a promising molecular target can combat the spread of retroviruses that can cause blood cancer and AIDS—but at the risk of leaving the host vulnerable to infections by other viral pathogens, a new Yale study ...
Dec 28, 2018
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