Oncology & Cancer

Boosting the immune response against cancer

T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...

Neuroscience

Study finds how the brain controls symptoms of sickness

When someone gets an infection, most people think it's the immune system kicking into gear when they feel some of the body's natural defenses like a fever, chills, or fatigue. What most people don't know is that it's actually ...

Neuroscience

Widespread brain receptor hides surprising mechanism of action

One of the most important molecules in the brain doesn't work quite the way scientists thought it did, according to new work by researchers at Columbia University Vagelos College of Physicians and Surgeons and Carnegie Mellon ...

Oncology & Cancer

Researchers identify new targets for immunotherapy in colon cancer

Colon cancer is one of the most common types of cancer. Particularly in advanced stages of disease, the treatment still largely relies on traditional chemotherapy. The new generation of cancer treatments, so-called immunotherapies, ...

Neuroscience

Hungry or full: It comes down to the atomic details

A protein—measuring just a few nanometers in size—acts as a molecular switch with a crucial role in determining whether we feel hungry or full. By determining of the protein's 3-D structure, researchers from Charité ...

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