Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...
Jun 21, 2012
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Researchers have discovered drugs that activate signaling pathways leading to specific adult brain cell types from stem cells in the mouse brain, according to a study publishing on 28 March in the open access journal PLOS ...
Mar 28, 2017
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Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically increases the ...
Dec 21, 2012
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A new research perspective titled "Using cancer proteomics data to identify gene candidates for therapeutic targeting" has been published in Oncotarget.
May 10, 2023
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Researchers from the Department of Chemistry and Molecular Biology at the University of Gothenburg have managed for the first time to obtain detailed information about the role of the protein metastasin in the spread of tumour ...
Apr 2, 2012
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A family of molecules developed at Carnegie Mellon University to break down pollutants in water is one step closer to commercial use. Study results published online in the journal Green Chemistry show that the molecules, ...
Jul 22, 2013
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They say the real crisis stems from current incentives that reward companies for developing large numbers of new drugs with few clinical advantages over existing ones.
Aug 7, 2012
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According to a new study carried out at the University of Eastern Finland, the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain. By converting drug ...
Sep 24, 2019
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There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that ...
Jan 16, 2019
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Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...
Apr 16, 2019
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