Alzheimer's disease & dementia

Possible pathway to new therapy for Alzheimer's disease

Researchers have uncovered an enzyme and a biochemical pathway they believe may lead to the identification of drugs that could inhibit the production of beta-amyloid protein, the toxic initiator of Alzheimer's disease (AD).

Neuroscience

Simple drug combination creates new neurons from neighboring cells

A simple drug cocktail that converts cells neighboring damaged neurons into functional new neurons could potentially be used to treat stroke, Alzheimer's disease, and brain injuries. A team of researchers at Penn State identified ...

Medications

Researchers test effectiveness of anti-opioid vaccine

Virginia Commonwealth University researchers are testing a vaccine against opioid abuse developed by the Scripps Research Institute in California. The vaccine is meant to block the effects of heroin and fentanyl in patients ...

Neuroscience

Brain implant could stop epilepsy seizures

For many people who suffer from neurological disorders, such as epilepsy, there are no viable treatment options. In our latest research, we developed an implantable device that may one day offer relief. We show that the implant ...

Diseases, Conditions, Syndromes

Key molecule for flu infection identified

After decades of research, a research team has discovered the key receptor molecule that enhances the infection of the influenza A virus, providing a novel target for anti-flu drug development.

Diseases, Conditions, Syndromes

Microglia are key defenders against prion diseases

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence ...

Oncology & Cancer

Structural studies help explain how cancer cells resist chemotherapy

In order to kill cancer cells, chemotherapy drugs must first make their way inside them. But cancer cells are shrewd, and some use molecular pumps to expel the drugs before they have a chance to work. New research from Rockefeller's ...

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