Researchers are zeroing in on the ultimate quest to regenerate insulin in pancreatic stem cells and replace the need for regular insulin injections.
Jan 2, 2024
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Many big pharma companies were able to roll out vaccines against SARS-CoV-2 in record time by retooling their existing experimental mRNA gene therapies to carry a new payload. Whereas these cancer vaccines originally coded ...
To identify potential therapeutic targets and preclinical drug candidates for the treatment of ovarian cancer, researchers led by Tan Li from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences ...
Nov 24, 2023
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146
The process researchers use to generate induced pluripotent stem cells (iPSCs)—a special type of stem cell that can be made in the lab from any type of adult cell—is time consuming and inefficient. To speed things up, ...
Sep 25, 2012
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A University of California, Irvine-led study suggests that the glucosyltransferase domain (GTD) is an ideal molecular target for therapeutic interventions for Clostridioides difficile infection (CDI). These findings may lead ...
Oct 22, 2021
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Scientists at Duke-NUS Medical School have identified a gene that controls the behavior of a specific type of cardiac macrophage responsible for excessive scarring during the early phases of common heart diseases or cardiomyopathies. ...
Dec 9, 2022
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An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has discovered a new pathway that may improve success ...
Aug 23, 2019
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Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes ...
Sep 21, 2011
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Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for ...
Jan 12, 2021
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A combination therapy pairing a small molecule inhibitor with monoclonal antibody immunotherapy improved patient outcomes for relapsed chronic lymphocytic leukemia (CLL), according to a Northwestern Medicine clinical trial ...
Aug 2, 2021
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