Medications

New approach could lead to a lifetime flu vaccine

If the virus that causes flu were an ice cream cone, then the yearly vaccine teaches the immune system to recognize just the scoop – chocolate one year, strawberry the next. As the virus changes each year, so too must the ...

Medical research

Humanization of antibodies targeting human herpesvirus 6B

A research group led by Professor Yasuko Mori (Division of Clinical Virology, Center for Infectious Diseases, Kobe University) has succeeded in humanization of mouse antibodies that can neutralize the infection caused by ...

Diseases, Conditions, Syndromes

Synthetic antibody rapidly protects mice and monkeys from Zika

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5th in the journal Molecular Therapy. Injections of synthetic DNA encoding the potent anti-Zika monoclonal ...

Cancer

New potential therapeutic target for pancreatic cancer discovered

Cancer cells demand enormous amounts of molecular "food" to survive and grow, and a study published March 27 online in Nature by researchers at The University of Texas MD Anderson Cancer Center may have identified a new approach ...

Diseases, Conditions, Syndromes

Chikungunya antibody set to enter clinical trial

A monoclonal antibody against the chikungunya virus developed by researchers at Vanderbilt University Medical Center is the first monoclonal antibody encoded by messenger RNA to enter a clinical trial.

page 1 from 23

Monoclonal antibodies

Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the generic drug name ends in -mab (see "Nomenclature of monoclonal antibodies").

This text uses material from Wikipedia, licensed under CC BY-SA