Arthritis & Rheumatism

Combo therapy not needed if low RA disease activity achieved

(HealthDay)—Once low rheumatoid arthritis (RA) disease activity is achieved with tocilizumab (TCZ) plus methotrexate (MTX), patients can discontinue MTX without significant disease worsening, according to a study published ...

Surgery

Laser improves QOL for breast telangiectasia due to radiation

(HealthDay)—Laser monotherapy improves health-related quality of life (HR-QOL) in female patients with radiation-induced breast telangiectasias (RIBT), according to a study published online Dec. 20 in Lasers in Surgery ...

Diabetes

Fat intake influences HbA1c-lowering effect in DPP4i therapy

(HealthDay)—For individuals with type 2 diabetes (T2D), fat intake may contribute to the deterioration of the hemoglobin A1c (HbA1c)-lowering effects in dipeptidyl peptidase-4 inhibitor (DPP4i) monotherapy, according to ...

Alzheimer's disease & dementia

Second Phase 3 study results for LMTX published

TauRx Therapeutics Ltd today reported the full results from its second Phase 3 clinical study of LMTX, the first tau aggregation inhibitor in Alzheimer's disease, published online in the Journal of Alzheimer's Disease.

Oncology & Cancer

Drug combo doesn't lengthen glioblastoma survival

(HealthDay)—In patients with progressive glioblastoma, treatment with lomustine plus bevacizumab does not confer a survival advantage over treatment with lomustine alone, according to a study published online Nov. 15 in ...

Oncology & Cancer

Lymphoma risk up with thiopurine, anti-TNF Tx in IBD

(HealthDay)—For patients with inflammatory bowel disease (IBD), the risk of lymphoma is increased with use of thiopurine monotherapy, anti-tumor necrosis factor (TNF) monotherapy, and combination therapy, according to a ...

Ophthalmology

Combo Tx superior for polypoidal choroidal vasculopathy

(HealthDay)—Combination therapy consisting of ranibizumab plus verteporfin photodynamic therapy (vPDT) is superior to ranibizumab monotherapy for treatment of eyes with polypoidal choroidal vasculopathy (PCV), according ...

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