Neuroscience

Mechanisms of how morphine relieves pain mapped out

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects.

Addiction

Syringe program user survey shows 'stunning' fentanyl surge

Use of the illicitly produced opioid fentanyl has surged by a "stunning" extent in Washington, said the lead researcher involved in a survey of nearly 1,000 people who use syringe-service program sites across the state.

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Morphine

Morphine (INN) (pronounced /ˈmɔrfiːn/) (MS Contin, MSIR, Avinza, Kadian, Oramorph, Roxanol) is a highly potent opiate analgesic psychoactive drug, is the principal active ingredient in Papaver somniferum (opium poppy, or simply opium), is considered to be the prototypical opioid. Like other opioids, e.g. oxycodone (OxyContin, Percocet, Percodan), hydromorphone (Dilaudid, Palladone), and diacetylmorphine (Heroin), morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly.

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