Genetics

ALS mystery illuminated by blue light

A joint research group in Japan has succeeded in reproducing key ALS symptoms in a small tropical fish by remotely controlling a disease-associated protein molecule using light illumination.

Genetics

Gene therapy can protect against ALS and SMA-related cell death

Researchers at Karolinska Institutet in Sweden and the University of Milan in Italy have identified a gene in human neurons that protects against the degeneration of motor neurons in the deadly diseases ALS and SMA. Gene ...

Neuroscience

Immunity key to motor neurone disease treatment

Customized immune-blocking medication may be the key to treating patients with motor neurone disease (MND), which currently has no cure and limited therapeutic options.

Neuroscience

New roles found for Huntington's disease protein

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.

Genetics

Scientists discover link between ALS genes

The enzyme Gemin3 was identified as the molecular 'bridge' between genes whose mutation or disruption causes amyotrophic lateral sclerosis (ALS), according to a new study in Nature's Scientific Reports from scientists at ...

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Motor neuron

In vertebrates, the term motor neuron (or motoneuron) classically applies to neurons located in the central nervous system (or CNS) that project their axons outside the CNS and directly or indirectly control muscles. Motor neuron is often associated with efferent neuron, primary neuron, or alpha motor neurons.

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