Genetics

New insights into the origins of spinal muscular atrophy

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

Diseases, Conditions, Syndromes

Discovery of a potential therapeutic target for ALS

University of Malta researchers have discovered a potential new drug target for amyotrophic lateral sclerosis (ALS), according to a new study published in the Neurobiology of Aging journal.

Medical research

Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

Medical research

Calming the destructive cells of ALS by two independent approaches

Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate ...

Neuroscience

How brains synchronize during cooperative tasks

Humans are social creatures. But what leads to them being this way? To fully understand how the brain gives rise to social behaviors, we need to investigate it during social encounters. Moreover, we need to analyze not only ...

Medical research

Studies point the way to broadly effective treatments for ALS

Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years. In the quest to find a cure for these patients, a team of researchers ...

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