A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination—when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts ...
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Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated. The research highlights a possible ...
Sep 17, 2021
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In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease. A study by the University of Basel has ...
Sep 16, 2021
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Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading ...
Sep 15, 2021
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Researchers at the National Institutes of Health, Johns Hopkins University, and others have published results of studies that map out the activity of genes, molecules, cells, and their interactions in specific types of multiple ...
Sep 09, 2021
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UCL researchers have shown that damage to the lining of the gut plays an important role in the development of rheumatoid arthritis, paving the way for a new approach to treating the disease.
Sep 06, 2021
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Innate immunity is the first line of defense against microbial infection. In response to RNA virus infection, mitochondrial antiviral signaling protein (MAVS) plays an important role in innate antiviral immune responses.
Sep 06, 2021
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A team of scientists led by Erik Storkebaum of Radboud University's Donders Institute have deciphered the molecular mechanism underlying a form of Charcot-Marie-Tooth (CMT) peripheral neuropathy. This disease affects both ...
Sep 03, 2021
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MUSC Hollings Cancer Center researchers discovered a novel mechanism showing how a certain gene mutation can allow tumors to evade detection by the immune system in colorectal cancer patients. The study, which was published ...
Sep 02, 2021
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Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target ...
Sep 02, 2021
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