An international team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at preventing replication of SARS-CoV-2, the virus that causes COVID-19. The work also underscores ...
Mar 24, 2021
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A transgenic mouse developed at Cincinnati Children's to model the deadly childhood immune disease HLH (hemophagocytic lymphohistiocytosis) may play a key role in saving lives during the COVID-19 virus pandemic.
May 28, 2020
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Neurobiologists at Heidelberg University have discovered how a special receptor at neuronal junctions that normally activates a protective genetic program can lead to nerve cell death when located outside synapses. Their ...
Oct 8, 2020
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A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive ...
Jul 1, 2020
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Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled ...
May 8, 2020
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Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, ...
Oct 29, 2020
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Maternal obesity impairs heart health and function of the fetus according to a new study in mice. The study, published in The Journal of Physiology found that maternal obesity causes molecular changes in the heart of the ...
May 12, 2022
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We may not think about it often, but our gut is home to a complex ecosystem of microorganisms that play a critical role in how we function. The system is delicate—one small change can cause a major shift in the microbiome, ...
Jul 31, 2020
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The concept of new bone formation via divalent cations is widely reported although the underlying mechanism of the process remains unclear. In a new report now published in Nature Communications, Wei Qiao and a team of scientists ...
Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, ...
Dec 21, 2021
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