The world's first mRNA vaccine has begun its rollout after being produced at unprecedented speed as part of the global effort to end the COVID-19 pandemic. A second one is hot on its heels. The two—one made by Pfizer/BioNTech ...
Dec 11, 2020
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Some of the most promising vaccines developed to combat COVID-19 rely on messenger RNA (mRNA)—a template cells use to carry genetic instructions for producing proteins. The mRNA vaccines take advantage of this cellular ...
Dec 11, 2020
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Developing and testing a new vaccine typically takes at least 12 to 18 months. However, just over 10 months after the genetic sequence of the SARS-CoV-2 virus was published, two pharmaceutical companies applied for FDA emergency ...
Dec 11, 2020
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"What is new about this vaccine is that it works using genetic code," says Research Scientist Sven Even Borgos at SINTEF. "This means that the vaccine instructs the body to make small and accurately selected components of ...
Nov 20, 2020
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As the weather cools, the number of infections of the COVID-19 pandemic are rising sharply. Hamstrung by pandemic fatigue, economic constraints and political discord, public health officials have struggled to control the ...
Nov 18, 2020
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German biotech company BioNTech and US pharmaceutical Pfizer announced on Monday promising early results from their phase 3 clinical trial for a vaccine against SARS-CoV-2, the virus that causes COVID-19.
Nov 10, 2020
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The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible ...
Oct 9, 2020
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Researchers at the Institute of Biology, Eötvös Loránd University (ELTE), Budapest, Hungary, studied the major types of neurons of the prefrontal cortex of the brain in an international collaboration. The research team ...
Oct 8, 2020
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Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that regulates levels of both aberrant and wild-type cellular RNAs. It also contributes to antiviral immunity against select plant and human RNA viruses. However, ...
Jul 24, 2020
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Imagine that we could instruct our bodies to make the drugs they need themselves. The gene technology that makes this possible is called mRNA therapy, which may become a major tool in the treatment of multiple diseases. Norwegian ...
May 20, 2020
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