Diseases, Conditions, Syndromes

FDA OKs second treatment for neuromyelitis optica spectrum disorder

(HealthDay)—Uplizna (inebilizumab-cdon) injection is now approved to treat neuromyelitis optica spectrum disorder (NMOSD) in patients who are anti-aquaporin-4 (AQP4) antibody positive, the U.S. Food and Drug Administration ...

Oncology & Cancer

FDA approves first-line therapy for peripheral T-cell lymphoma

(HealthDay)—The U.S. Food and Drug Administration on Friday expanded approval for the use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with specific types of peripheral ...

Oncology & Cancer

Adcetris FDA approval expanded to include later-stage Hodgkin's

(HealthDay)—U.S. Food and Drug Administration approval of Adcetris (brentuximab vedotin) has been expanded to include adults with untreated stage III or IV classical Hodgkin's lymphoma, the agency said Tuesday in a news ...

Diseases, Conditions, Syndromes

Researchers shed light on pathway from virus to brain disease

Why people on immunosuppressant drugs for autoimmune conditions have a higher incidence of an often-fatal brain disease may be linked to a mutation in a common virus, according to researchers at Penn State College of Medicine.

Diseases, Conditions, Syndromes

Vaccination on the horizon for severe viral infection of the brain

Researchers from the University of Zurich and the University Hospital Zurich reveal possible new treatment methods for a rare, usually fatal brain disease. Thanks to their discovery that specific antibodies play a key role ...

Medications

Dimethyl fumarate linked to development of PML

(HealthDay)—An active ingredient in some psoriasis and multiple sclerosis medications, dimethyl fumarate, has been linked to two cases of progressive multifocal leukoencephalopathy (PML), according to two letters published ...

Medications

FDA investigating PML in patient taking MS drug

(HealthDay)—The U.S. Food and Drug Administration is investigating the possible association between a rare brain infection and the multiple sclerosis (MS) drug Gilenya (fingolimod), according to a drug safety alert issued ...

Medical research

Study builds dossier on JC polyomavirus

A new study shows that common mutant forms of the deadly JC polyomavirus are not responsible for the pathogen's main attack, which causes a brain-damaging disease in immunocompromised patients called progressive multifocal ...

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