Diseases, Conditions, Syndromes

Enhanced oral uptake of exosomes opens cell therapy alternative

Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed ...

Medical research

Study reveals surprising variability of muscle cells

Usually, each cell has exactly one nucleus. But the cells of our skeletal muscles are different: These long, fibrous cells have a comparatively large cytoplasm that contains hundreds of nuclei. But up to now, we have known ...

Medical research

Damaged muscles don't just die, they regenerate themselves

A research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells. While attempting to identify the proteins ...

Medical research

Drugging the undruggable: A treatment path for muscular dystrophy

Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy (DMD), a rare genetic disease for which there is currently no cure or treatment, by targeting an enzyme that had been considered 'undruggable.' ...

Diseases, Conditions, Syndromes

'Crosstalk' between muscle and spleen in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is the most common muscle disease in children and is passed on by X-linked recessive inheritance. Characteristic is a progressive muscular atrophy. The disease often results in death before ...

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