Medical research

Neutral mutants can prevail in gut microbiota, enhancing diversity

Scientists at EPFL and Sorbonne propose a new model of the diversity and evolution of gut bacteria that shows how the gut environment helps neutral mutations become prevalent, with significant potential implications on health ...

Parkinson's & Movement disorders

Parkinson's disease mutation misdirects iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...

Oncology & Cancer

New treatment options for the deadliest of cancers

A new way to target a mutant protein which can cause the deadliest of cancers in humans has been uncovered by scientists at the University of Leeds.The mutated form of the RAS protein has been referred to as the "Death Star" ...

Medical research

Enhanced autophagy could help treat diabetes

Enhancing autophagy—the cellular process that breaks down and removes unneeded components—in fat tissue could help treat diabetes, according to a Northwestern Medicine study published in Cell Reports.

Genetics

Cancer 'guardian' breaks bad with one switch

A mutation that replaces a single amino acid in a potent tumor-suppressing protein turns it from saint to sinister. A new study by a coalition of Texas institutions shows why that is more damaging than previously known.

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